The Iranian Parliament voted on Sunday to remove the minister of economic affairs and finance, Masoud Karbasian, from office, state media said, amid a sharp fall in the rial currency and a deterioration in the economic situation.
In early August Iranian lawmakers voted out the minister of labour and last month President Hassan Rouhani replaced the head of the central bank.
A total of 137 members of parliament voted for Karbasian's removal, state media said, while 121 members voted in favour of him remaining in office.
Protests linked to the tough economic situation in the country began last December, spreading to more than 80 cities and towns and resulting in 25 deaths.
Sporadic protests, led by truck drivers, farmers, and merchants in Tehran's bazaar, have continued regularly since then and have occasionally resulted in violent confrontations with security forces.