Kieran Gibbs Nacho Monreal Arsenal
Arsenal left-backs Kieran Gibbs and Nacho Monreal are both doubts for the English Premier League game against SouthamptonReuters

Left-backs will be the worry of the day, it seems, for Arsenal when they host Southampton in the English Premier League on Wednesday.

Arsene Wenger has concerns over both Nacho Monreal, who had to be taken off in the first half against West Brom on Saturday, and Kieran Gibbs ahead of the Premier League showdown against the dangerous Saints.

Monreal and Gibbs will both be assessed prior to the game before taking a decision, while the same goes for Alex Oxlade-Chamberlain, who is also struggling with a knock as Arsenal's injury worries just refuse to cease.

"We have some question marks about Monreal, about Gibbs and about Oxlade-Chamberlain," said Wenger on Tuesday. "They have tests this morning. Everybody else looks to be available."

Laurent Koscielny made a welcome return from an Achilles problem against West Brom, showing just who much Arsenal had missed him, and Wenger is hopeful the France international defender is well and truly over his injury worries.

"We have Koscielny, who has just come back after a long time, so we'll see how he responds this morning [to training]," added Wenger. "Let's hope he will be back for a long period.

"He had two tendons which were bad. The left has gone completely and the right is still a little bit there so, if he has no reaction, he can cope with it. If he has a reaction, you have to be cautious."

Arsenal, though, will have to make do without their first choice goalkeeper Wojciech Szczesny, who is yet to recover from the hip injury picked up against Manchester United ten days ago.

"Szczesny is still out," said Wenger. "[He could return in] maybe three or four days, or the end of the week. We don't know yet."

With David Ospina still recovering from his long-term problem, it means another run-out in goal for Emiliano Martinez, who has done pretty well so far.

Ospina, though, could come back into contention from next week, along with Mathieu Debuchy, one of the players Arsenal have missed the most ever since he injured his ankle in September.

"Debuchy is one week away," Wenger said. "He is training. Could he be involved next week? Certainly. Ospina is as well one week [away]."

There was no update on Theo Walcott, who has seen his comeback from a serious knee injury disrupted by a groin problem, but the forward is not expected to feature.

However, Yaya Sanogo is now fit after his goalscoring exploits against Borussia Dortmund, but the Frenchman will struggle to make it to the starting lineup with Olivier Giroud, Danny Welbeck and Alexis Sanchez all buzzing.

The midfield will still be without Jack Wilshere, Mikel Arteta, Abou Diaby and Mesut Ozil.