Manchester United travel to the north-eastern part of England to take on Newcastle United as they look to strengthen their current position in the Premier League.
Apart from their draw and defeat to West Ham and Swansea City respectively, the Red Devils have been doing pretty well in the Premier League of late, sitting in the fourth place after recording four wins in their last six fixtures.
They were a little shaky in their last fixture against Sunderland, but they still managed to record a win courtesy of a second-half brace from United captain Wayne Rooney.
United were able to record a comfortable 3-1 victory over Newcastle United during the two' sides meeting in the reverse fixture at Old Trafford. And van Gaal feels the Red Devils were excellent during that game.
"I have seen the match again, as always before a match, and I think we played a good match. The 3-1 win was well deserved – we could have scored more, but it is always like that," the Dutchman told United's official website.
Still the former Bayern Munich boss says he is expecting "a very tough game" at St James' Park.
"Newcastle always play at a very high rhythm, exerting a lot of energy. They want to play football and I like that. Their fans always get behind the team so I'm expecting a very tough game."
Meanwhile, Newcastle will be feeling a little better after beating Aston Villa following their demoralising 0-5 defeat against Manchester City on 21 February.
Despite getting off to a very poor start to the 2014/15 season, failing to record a single win in their first seven Premier League fixtures, the Magpies have managed to recover pretty well as they are currently far away from the relegation in the 11th position.
Although the Magpies are not expected to beat Manchester United, Newcastle boss John Craver feels that his side can cause an upset on Wednesday.
"We looked at their record away from home and it is not great," says Carver, according to Manchester United's official website. "They have some super players going forward but they are vulnerable in certain areas and hopefully we can exploit that. You have to find a way of upsetting them."
Newcastle defender Daryl Janmaat despite admitting that United are a "big side", also feels that the Magpies can do well against the Red Devils on Wednesday.
"The pressure will be more on them than us. We got the three points out of our last game which was crucial for us," the Dutchman told Newcastle's official website. "Those points will build our positivity as a team and we can now be more confident to play Manchester United."
"We want the win, we want the three points and we will do everything that we can to get them."
Newcastle: Krul; Janmaat, Coloccini, Williamson, Taylor; Abeid, Sissoko; Ameobi, Perez, Obertan; Cisse
Man United: De Gea; Valencia, Smalling, Rojo, Shaw; Blind, Herrera; Young, Rooney, Di Maria; Falcao
Where to Watch Live
The EPL match is scheduled for 2pm GMT (7:30am IST, 9am ET), starting with live coverage in India on Star Sports 4 in India. The game can also be watched via live streaming online in India on StarSports.com.
Viewers in the UK can catch the match live on BT Sports 1, while the live streaming option is on BT Sports Online. There will be no live telecast of the game in the US, but viewers can stream the action online on NBC Sports Live Extra.
Audience in the Middle East and North Africa can watch the game via live streaming online on Bein Sports Connect, while South Africa and Sub Saharan Africa viewers can do the same on SuperSport online. Australia viewers can watch the game on Fox Sports and live stream it on Fox Sports On Demand.