George Clooney
U.S. actor George Clooney and his wife Amal Alamuddin.Reuters

The absence of Brad Pitt and his wife Angelina Jolie at George Clooney's wedding to Amal Alamuddin over the weekend had many wondering if the actors had a falling out, especially as it was earlier reported that Pitt would be Clooney's best man.

But reports have it that their bromance is still alive, and their personal equation is as strong as ever, although they don't meet up quite often. In an interview with GQ Pitt noted that while he was considered to be "unreachable," Clooney was a much friendlier person, reported Mirror.

He said: "Well, you know, George is extremely accessible. He's one of our best representatives. He's funny as s***. He's a joy to be around. I guess maybe I'm more of a miserable b******.

"I'm a bit of a loner you know? I'm more quiet by nature. And coming from, you know, hillbilly country, I'm probably more reserved," he added.

Regarding their much-talked-about friendship, Clooney too previously gushed to The Hollywood Reporter stating that Pitt was a great guy to hang around with.

"Brad is one of the great guys," he said. "We're good friends, but it's different from what people think, meaning we don't spend a lot of time together. He has been to my home in Como; we motorcycle together."

So where exactly was Pitt, with whom Clooney has shared screen space in four films, and Jolie at the time of the much awaited wedding of the year? As per reports, the couple was filming "By the Sea" in Malta, an island off the coast of Italy, when several guests including Richard Kind, Matt Damon, Bono, Bill Murray, John Krasinski, Emily Blunt and Cindy Crawford and husband Rande Gerber attended their friend's nuptials.

The Clooney-Alamuddin wedding was a private ceremony, where the groom wore an Armani suit while the bride chose an Oscar de la Renta number. The ceremony was officiated by the actor's friend and former Mayor of Rome, Walter Veltroni.

Also noticeably absent were Clooney's friends and fellow co-stars Sandra Bullock, Julia Roberts and Ben Affleck.

Affleck, who was promoting his new movie "Gone Girl" in New York City told ET Canada: "Some people have to work and everybody else gets to be in Venice. But [George] found a great girl and I'm happy for them. I wish them the best."