An environment friendly hand sanitizer that is gentle on the hands and does not dry them, will soon be available in the market. The alcohol-free, aqueous, non-inflammable and non-toxic hand sanitizer has been developed using silver nanoparticles by a Pune-based start-up.

Recurrent drying up of hands due to repeated application of hand sanitizers remained a challenge that people faced during the COVID 19 pandemic.

sanitizer

The hand sanitizer developed by Weinnovate Biosolutions prolongs antimicrobial activity, thus, obviating the need for repeated applications. Silver nanoparticles give slow and sustained release of silver ions to kill microorganisms that come in contact. It can be stored in ambient conditions.

The new sanitiser has successfully completed Central Drugs Standards Control Organisation (CDSCO) approved clinical trial for the hand sanitizer and demonstrated high efficiency in killing viruses.

Weinnovate Biosolutionswas supported by CAWACH 2020 grant of National Science and Technology Entrepreneurship Development Board (NSTEDB) under the Department of Science and Technology (DST) and incubated at Entrepreneurship Development Centre (Venture Centre), Pune.

The makers have developed the colloidal silver solution-based hand sanitiser exploiting the ability of the silver nanoparticles to prevent the synthesis of viral negative-strand RNA and viral budding.

"We are very confident of the study outcomes and waiting to get the license for our hand sanitiser formulation from CDSCO, India. We are sure that such innovation will push India towards its 'Atmanirbhar Bharat' mission and make India a self-sustained nation to face such pandemics in future", said Dr. Anupama Engineer, Cofounder of Weinnovate Biosolutions.

Silver nanoparticles have been found to be an effective antiviral which act against many deadly viruses like HIV, Hepatitis B, Herpes simplex virus, Influenza virus, and so on. Recent reports have suggested the role of Glutathione capped-Ag2S NCs (Silver nanoclusters) in inhibiting the proliferation of Coronavirus by preventing the synthesis of viral negative-strand RNA and viral budding.

The  technology of these sanitisers of Weinnovate Biosolutions is based on colloidal silver to arrest Covid -19 spread by blocking the RNA replication and infectivity by blocking the surface glycoproteins. A study to evaluate the efficacy of hand sanitiser on different types of viruses is also currently underway by the group.