Inter Milan and Wolfsburg face each other in the second leg round of 16 of the Europa League at the San Siro on Thursday.
The Nerazzurri are currently not in a very good position to progress the final eight of the Europa League following their 1-3 defeat at Wolfsburg in the first leg.
Inter Milan claimed the lead after only five minutes through Rodrigo Palacio, but Naldo soon equalled before a brace from Kevin De Bruyne saw Wolfsburg record a comfortable win over the Serie A side.
Apart from the Europa League, Inter Milan have not been in the best of forms in the Serie A, but manger Roberto Mancini insists that he is "optimistic" of his side's chances of progressing to the quarter-finals of the European competiton.
"I'm always optimistic," said Mancini, according to Goal. "We have to go for it, we'll need a big night. We need to use our heads and not be too hurried because goals can come at any time."
"The players need to relax, anything can happen in 90 minutes. We need to play well and be lucky."
Inter Milan had made a lot of comebacks in Europe over the years and Mancini feels that they may be doing the same this season.
"I believe in us. In all the cups Inter have won there were sensational comebacks and an evening without mistakes - sooner or later that has to happen."
Meanwhile, Wolfsburg will be full of confidence ahead of their clash against Inter Milan, having defeated the Serie A side comprehensively in the first leg.
They domestic form this season has also been good as they are currently second in the Bundesliga and in the quarter-finals of the DFB-Pokal.
There are suggestions that Wolfsburg will have a tough time in Italy, but Wolfsburg Dieter Hecking insists that his team are not afraid of facing Inter at the San Siro.
"We're not afraid. We go into this game with respect - which is appropriate I think - but there is no fear because we know that we are good," said Hecking, according to All Sports. "We brought along a good result and I think we have a slight advantage, like 51-49."
Inter Milan: Carrizo; D'Ambrosio, Ranocchia, Juan, Santon; Guarin, Medel, Hernanes; Icardi, Shaqiri, Icardo
Wolfsburg: Benaglio; Vierinha, Klose, Knoche, Rodriguez; Guilavogui, Luiz Gustavo; Caligiuri, De Bruyne, Schurrle; Dost
Where to Watch Live
The game is scheduled for an 9:05pm local time (1:35am IST, 8:05pm GMT, 4:05pm ET) start, with live coverage on Ten Sports in India. The match can also be watched via live streaming online on Ten Sports Live.
Catch the action in the UK live on ITV 4, with an option to live stream the match online on ITV Player. The US viewers can watch the game live on Fox Sports 1 or online on Fox Soccer 2Go. Audience in Canada can see the tie via live stream on Sportsnet World.
Viewers in Italy can watch the match live on Premium Calcio 3, while German viewers can do the same on Sky Sports 1 and Sky Sports 2.