Arsenal can afford only one result really in this North London Derby at White Hart Lane against Tottenham, otherwise they will not only be staring at the end of St. Totteringham's Day, they will also miss out on their greatest chance of winning the English Premier League title since the move to the Emirates Stadium from Highbury.
Having managed two abysmal performances over the past week – against Manchester United and Swansea City – Arsenal need to show their bouncebackability powers and come away with all three points against Spurs on Saturday.
This North London Derby has been hyped up as the biggest in the Premier League era, considering the result could have a big effect on the eventual winners of the title, and Wenger is aware of the fact that his team cannot afford to trip up, yet again, on the big stage, when the pressure is right on them.
"It is normal [to have the hype] because both teams are fighting up there," Wenger told the club's official website. "The biggest ever? I don't know the full history exactly but it is a big game, that is for sure. It is a very important one for both teams and we also have a good record against Tottenham and we want to keep that up.
"What makes the difference on (derby) day is that fraction of belief, commitment and togetherness that gives a team a supplement of force. That is what we want to show.
"(We won there this season and) what you have done can always help you to know that you can do it. Let's focus on the process and defend well together, attack well together, play our passing game and be ready for a fight for 90 minutes. That might be the key in the end."
What is worrying from Arsenal's point of view is the fact that Wenger still thinks his team did not play that badly against Manchester United or that a lack of luck was the reason behind their 2-1 loss to Swansea City. While, to a certain extent, the latter excuse might be true, it remains just that – an excuse.
Arsenal had enough chances in the Swansea City game to put it to bed even before the equaliser came – yes, via an obvious foul – and the players, plain and simple, choked, failed to cope with the pressure.
That cannot happen against Spurs, who have gone from strength to strength, playing like machines so exceptionally controlled by Mauricio Pochettino. Tottenham tripped up a little when they lost to West Ham, when a win would have taken them to the top of the table, but this Spurs side have shown enough quality this season to earn their right to be called the favourites going into this game.
"All that matters now is what this game means," Pochettino told his club's official website. "It's a tough game, Arsenal are a very good team but we are sure that we will arrive in a very good condition to compete."
Team news: Tottenham: Jan Vertonghen and Clinton Njie remain on the treatment table, but Dele Alli and Moussa Dembele is expected to make it for this big North London derby.
Arsenal: Wenger was dealt a big blow when Petr Cech was ruled out of this match, and a further three-four weeks. Laurent Koscielny will also miss the clash, along with long-term absentees Mikel Arteta, Santi Cazorla, Tomas Rosicky and Jack Wilshere.
Expected lineups: Tottenham: Lloris; Walker, Alderweireld, Wimmer, Rose; Dier, Mason; Lamela, Alli, Eriksen; Kane.
Arsenal: Ospina; Bellerin, Mertesacker, Gabriel, Monreal; Coquelin, Ramsey; Campbell, Ozil, Sanchez; Giroud.
Where to Watch Live
The North London Derby is scheduled for a 12.45 pm GMT (7.45 am ET, 6.15 pm IST) start. Live TV coverage of the match in India will be on Star Sports 4 and Star Sports HD4, while the match can also be viewed via live streaming online on Starsports.com, Hotstar.
The Premier League match between Tottenham and Arsenal will be shown live in the UK and Ireland on BT Sport 1, with the live stream option on Watch BT Sport. Audience in the region can also listen to the match live on BBC Radio 5 Live.
NBCSN will show the game live in the US, while the action can also be live streamed on NBC Sports Live Extra. Audience in Canada can watch the action live on TSN, with the live streaming option on TSN TV.
Viewers in Singapore can watch the match live on 102 mio, with live coverage of the game in Thailand on CTH. Bein Sports Arabia 2 will broadcast Spurs vs Arsenal in the Middle East and North Africa, while the action can also be live streamed on Bein Sports Connect.