This is a match neither can lose, but lose one of them must as England and Wales clash in a mammoth 2015 Rugby World Cup Pool A match at Twickenham on Saturday.
Both sides won their opening matches, without really convincing entirely, and England and Wales will know only their best performance will do for this second match.
With Australia also in the same pool, and only two teams moving to the quarterfinals, this match will be one of the key ones that decide the couple of teams who will eventually qualify for the knockout rounds.
England coach Stuart Lancaster, who clearly wasn't too happy with his team's performance against Fiji, despite the win, has made quite a few changes to his team for the match against Wales, chief of them being George Ford making way for Owen Farrell, while the raw Sam Burgess takes up his position at centre, which means a matchup against the experienced Jamie Roberts.
"The game will be judged a success if we win," Lancaster was quoted as saying by BBC Sport. "If we lose I will be questioned. Clearly my selection heightens it.
"We need to have good defenders to stop Wales on the gain-line. Sam's a good and powerful defender. But also I think he offers us a threat in attack. We don't always have to use the threat that he is. Sometimes you can bypass him."
When you bring in someone inexperienced like Burgess, the opponents are inevitably going to target you, and while Wales coach Warren Gatland insisted the team will concentrate on the England team as a whole, there is little doubt that Burgess will be put under extra pressure, especially early in this World Cup contest.
"We won't be trying to single out Sam Burgess at all," Gatland said. "We will be going out there to smash him like everyone else. He's got inexperience at rugby union, but not at big occasions.
"We're not rubbing our hands together about one player thinking there's a weakness there - that is not the way we look at it. When you underestimate a player, it comes back to bite you."
While Gatland is under no illusion regarding the importance of this Pool A match, he refrained from the mind games that usually pour out from both sides before the game.
"I don't want to play any kind of mind games," Gatland added. "It is just about this weekend and the respect I have for this English team. Let's hope it's a great game and afterwards, for whoever wins or loses, I'd like both teams to have a beer and a chat.
"There's huge respect. May the best team win by playing the best rugby. Let's hope there's not a controversial decision. Let the rugby do the talking."
Teams: England: Mike Brown, Anthony Watson, Brad Barritt, Sam Burgess, Jonny May, Owen Farrell, Ben Youngs, Joe Marler, Tom Youngs, Dan Cole, Geoff Parling, Courtney Lawes, Tom Wood, Chris Robshaw, Billy Vunipola.
Replacements: Rob Webber, Mako Vunipola, Kieran Brookes, Joe Launchbury, James Haskell, Richard Wigglesworth, George Ford, Alex Goode.
Wales: Liam Williams, George North, Scott Williams, Jamie Roberts, Hallam Amos, Dan Biggar, Gareth Davies, Gethin Jenkins, Scott Baldwin, Tomas Francis, Bradley Davies, Alun Wyn Jones, Dan Lydiate, Sam Warburton, Taulupe Faletau.
Replacements: Ken Owens, Aaron Jarvis, Samson Lee, Luke Charteris, Justin Tipuric, Lloyd Williams, Rhys Priestland, Alex Cuthbert.
Where to Watch Live
England vs Wales is scheduled for an 8 pm BST (12.30 am IST, 3 pm ET) start. The Rugby World Cup Pool A match will be shown live in India on Sony Six.
Viewers in the UK and Ireland can watch the match live on ITV1, with the live stream option on ITV Player.
Sky Sport will show the match live in New Zealand, while the action can also be watched via live streaming on Sky Go NZ.
Viewers in Australia can watch Wales play England live on Fox Sports 2, with the live stream option on Foxtel Play.
Match 16 of the 2015 Rugby World Cup will be shown live in South Africa on SuperSport, while the live stream option is on SuperSport Live Video.
Audience in the USA can watch the rugby World Cup opening match live onUniversal Sports, while the big game can also be live streamed on Universal Sports Online.
Audience in Canada can watch the game live on TSN, while the action can also be live streamed on TSN TV.